Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

Jolanta Grembecka, Shihan He, Aibin Shi, +9

Nature Chemical Biology

Hematological MalignancyTumor BiologyMixed-phenotype Acute LeukemiaMalignant Blood DisorderMenin-mll Inhibitors +7

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia

Aibin Shi, Marcelo J. Murai, Shihan He, +7

Blood

Synthesis and anti-breast cancer activities of substituted quinolines

Aibin Shi, Thu Annelise Nguyen, Srinivas K. Battina, +4

Bioorganic & Medicinal Chemistry Letters

PharmacologyAnti-breast Cancer ActivitiesSynthetic ChemistryNatural Product Synthesis

Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule <i>in vitro</i> and <i>in vivo</i>

Hyun‐Seok Hong, Sandeep Rana, Lydia M. Barrigan, +5

Journal of Neurochemistry

Small Beta-amyloidAbeta AggregatesMolecular BiologyMolecular PharmacologyAlzheimer's Disease +14

Antitumor effect of substituted quinolines in breast cancer cells

Gunjan Gakhar, Takahiro Ohira, Aibin Shi, +2

Drug Development Research

Breast OncologyGap JunctionCancer BiologySubstituted QuinolinesTumor Biology +14

Preparation of chitosan-g-polylactide graft copolymers via self-catalysis of phthaloylchitosan and their complexation with DNA

Li Liu, Aibin Shi, Shengrong Guo, +3

Reactive and Functional Polymers

EngineeringPolymer ScienceChitosan-g-polylactide Graft CopolymersBiomolecular EngineeringPolymer Reaction +2

Protection of retinal cells from ischemia by a novel gap junction inhibitor

Satyabrata Das, Dingbo Lin, Snehalata Jena, +5

Biochemical and Biophysical Research Communications

Retinal CellsOcular DiseaseRetinaOphthalmologyMedicine +4

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

Hyun-Seok Hong, Izumi Maezawa, Madhu S. Budamagunta, +9

Neurobiology of Aging

Alzheimer's DiseaseEngineeringMedicineAmyloid Imaging AgentsNeurochemical Biomarkers +4

Combination of Nanogel Polyethylene Glycol-Polyethylenimine and 6(hydroxymethyl)-1,4-anthracenedione as an Anticancer Nanomedicine

Chanran Ganta, Aibin Shi, Srinivas K. Battina, +5

Journal of Nanoscience and Nanotechnology

Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels

Jianyu Lu, Angelo Aguilar, Bende Zou, +7

Bioorganic & Medicinal Chemistry

Antagonistic ActivityBiochemistryMedicineNatural SciencesPharmacological Agent +6