Concepedia

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

Jolanta Grembecka, Shihan He, Aibin Shi, Trupta Purohit, Andrew G. Muntean, Roderick J. Sorenson, Hollis D. Showalter, Marcelo J. Murai, Amalia Marie Belcher, Thomas Hartley,

Nature Chemical Biology · 2012 · 449 citations · 33 references

DOI

Concepts

References

33

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

Todd R. Golub, Donna K. Slonim, Pablo Tamayo et al. · Science · 1999 · 11.6K citations

, , +16

Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1

Settara C. Chandrasekharappa, Siradanahalli C. Guru, Pachiappan Manickam et al. · Science · 1997 · 2.1K citations

, , +17

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

Scott A. Armstrong, Jane Staunton, Lewis B. Silverman et al. · Nature Genetics · 2001 · 1.7K citations

, , +16

Group Epitope Mapping by Saturation Transfer Difference NMR To Identify Segments of a Ligand in Direct Contact with a Protein Receptor

Moriz Mayer, Bernd Meyer · Journal of the American Chemical Society · 2001 · 1.2K citations

, , +17