Marcelo J. Murai

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

Jolanta Grembecka, Shihan He, Aibin Shi et al. · Nature Chemical Biology · 2012 · 449 citations

Medicine, Molecular Biology, Oncology +12

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia

Aibin Shi, Marcelo J. Murai, Shihan He et al. · Blood · 2012 · 200 citations · Full text

Medicine, Cancer Biology, Molecular Biology +8

Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein

Marcelo J. Murai, M. Chruszcz, Gireesh Reddy et al. · Journal of Biological Chemistry · 2011 · 108 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +4

The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia

Nancy Pinnell, Ran Yan, Hyo Je Cho et al. · Immunity · 2015 · 81 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Periostin Responds to Mechanical Stress and Tension by Activating the MTOR Signaling Pathway

Luciana K. Rosselli‐Murai, Luciana O. Almeida, Chiara Zagni et al. · PLoS ONE · 2013 · 62 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +14