Qingyian Liu

Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of <i>N</i>-Aryl Cinnamides

Elizabeth M. Doherty, Christopher Fotsch, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2004 · 102 citations · Full text

Transient Receptor Potential, Molecular Pain, Pharmacotherapy +16

Discovery of TRPM8 Antagonist (<i>S</i>)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine

Daniel B. Horne, Kaustav Biswas, James Brown et al. · Journal of Medicinal Chemistry · 2018 · 60 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Trpm8 Antagonist +15

The discovery of 2-anilinothiazolones as 11β-HSD1 inhibitors

Chester Yuan, David J. St. Jean, Qingyian Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 41 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Target +7

Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2

Liping H. Pettus, Matthew P. Bourbeau, Jodi Bradley et al. · Journal of Medicinal Chemistry · 2019 · 33 citations · Full text

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease

Jian Jeffrey Chen, Qingyian Liu, Chester Yuan et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 29 citations · Full text

Alzheimer's Disease, Medicine, 2-Aminooxazoline 3-Azaxanthenes +9