James Brown

A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization

Thomas S. Walter, Jonathan M. Diprose, Chris Mayo et al. · Acta Crystallographica Section D Biological Crystallography · 2005 · 250 citations · Full text

Natural Sciences, Biophysics, Molecular Biophysics +14

Structure of the fungal β‐glucan‐binding immune receptor dectin‐1: Implications for function

James Brown, Christopher A. O’Callaghan, Andrew S. J. Marshall et al. · Protein Science · 2007 · 187 citations · Full text

Life Sciences, Biochemistry, Immunology +17

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng, Ted Judd, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2011 · 141 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Methods for Protein Characterization by Mass Spectrometry, Thermal Shift (ThermoFluor) Assay, and Multiangle or Static Light Scattering

Joanne E. Nettleship, James Brown, Matthew R. Groves et al. · Methods in molecular biology · 2008 · 137 citations

Life Sciences, Biochemistry, Molecular Biology +16

A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results

James Brown, Thomas S. Walter, L. Carter et al. · Journal of Applied Crystallography · 2003 · 131 citations · Full text

Natural Sciences, Biochemistry, Crystal Structure +16