Jeffrey S. Carter

Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation

Graciela B. Arhancet, Daniel P. Walker, Sue Metz et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design

Daniel P. Walker, Graciela B. Arhancet, Hwang‐Fun Lu et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Thiol and hydroxamic acid containing inhibitors of endothelin converting enzyme

Stephen R. Bertenshaw, John J. Talley, Roland S. Rogers et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 18 citations

Life Sciences, Biochemistry, Pharmacology +8

Homo-timeric structural model of human microsomal prostaglandin E synthase-1 and characterization of its substrate/inhibitor binding interactions

Xing Li, Ravi G. Kurumbail, Ronald B. Frazier et al. · Journal of Computer-Aided Molecular Design · 2008 · 18 citations

Life Sciences, Biochemistry, Pharmacology +16

Amino acid derivatives that stabilize secondary structures of polypeptides—IV. Practical synthesis of 4-alkyamino-3-cyano-azabicyclo[3.2.1.]oct-3-enes (Ben derivatives) as γ-turn templates

D. S. KEMP, Jeffrey S. Carter · Tetrahedron Letters · 1987 · 17 citations

Natural Sciences, Chemistry, Molecular Biology +14