Ravi G. Kurumbail

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

Ravi G. Kurumbail, Anna M. Stevens, James K. Gierse et al. · Nature · 1996 · 1.9K citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure and function of cytochromes P450:a comparative analysis of three crystal structures

Charles A. Hasemann, Ravi G. Kurumbail, Sekhar Boddupalli et al. · Structure · 1995 · 693 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Molecular Docking and High-Throughput Screening for Novel Inhibitors of Protein Tyrosine Phosphatase-1B

Thompson N. Doman, Susan L. McGovern, Bryan J. Witherbee et al. · Journal of Medicinal Chemistry · 2002 · 467 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385

Scott W. Rowlinson, James R. Kiefer, Jeffery J. Prusakiewicz et al. · Journal of Biological Chemistry · 2003 · 347 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life

Jane L. Wang, David C. Limburg, Matthew J. Graneto et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 335 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15