Scott W. Rowlinson

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

Shira Cramer, Achinto Saha, Jinyun Liu et al. · Nature Medicine · 2016 · 521 citations

Systemic Depletion, Inase Increases, Pathology +7

Oxygenation of the Endocannabinoid, 2-Arachidonylglycerol, to Glyceryl Prostaglandins by Cyclooxygenase-2

Kevin R. Kozak, Scott W. Rowlinson, Lawrence J. Marnett · Journal of Biological Chemistry · 2000 · 391 citations · Full text

Inflammation, Anti-inflammatory, Oxysterol +13

A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385

Scott W. Rowlinson, James R. Kiefer, Jeffery J. Prusakiewicz et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +16

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

Ioannis Poursaitidis, Xiaomeng Wang, Thomas Crighton et al. · Cell Reports · 2017 · 282 citations · Full text

Apoptosis, Cell Death, Redox Biology +25

Structural insights into the stereochemistry of the cyclooxygenase reaction

James R. Kiefer, Jennifer L. Pawlitz, Kirby T. Moreland et al. · Nature · 2000 · 271 citations

Aldehyde Dehydrogenase, Biochemistry, Natural Sciences +3