Jennifer L. Pawlitz

A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385

Scott W. Rowlinson, James R. Kiefer, Jeffery J. Prusakiewicz et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +16

The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life

Jane L. Wang, David C. Limburg, Matthew J. Graneto et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 324 citations · Full text

Medicinal Chemistry, Novel Benzopyran Class, Favorable Human Half-life +11

Structural insights into the stereochemistry of the cyclooxygenase reaction

James R. Kiefer, Jennifer L. Pawlitz, Kirby T. Moreland et al. · Nature · 2000 · 271 citations

Aldehyde Dehydrogenase, Biochemistry, Natural Sciences +3

Synthesis, Crystal Structure, and Activity of Pyrazole-Based Inhibitors of p38 Kinase

Matthew J. Graneto, Ravi G. Kurumbail, Michael L. Vazquez et al. · Journal of Medicinal Chemistry · 2007 · 64 citations · Full text

The novel benzopyran class of selective cyclooxygenase-2 inhibitors-part I: The first clinical candidate

Jane L. Wang, Jeffery Carter, James R. Kiefer et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 48 citations · Full text

Medicinal Chemistry, Novel Benzopyran Class, Biochemistry +12