François Lenoir

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 929 citations

Life Sciences, Cell Biology, Oncology +16

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Jorge Fortanet, Christine Hiu-Tung Chen, Ying-Nan P. Chen et al. · Journal of Medicinal Chemistry · 2016 · 291 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Identification of NVP-TNKS656: The Use of Structure–Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor

Michael D. Shultz, Atwood K. Cheung, C.A. Kirby et al. · Journal of Medicinal Chemistry · 2013 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Role of the Acidity of N-Heteroaryl Sulfonamides as Inhibitors of Bcl-2 Family Protein–Protein Interactions

B. Barry Touré, Karen Miller‐Moslin, Naeem Yusuff et al. · ACS Medicinal Chemistry Letters · 2013 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

The role of the symbiotic fungus in the digestive metabolism of several species of fungus-growing termites

Corinne Rouland, François Lenoir, Mario Lepage · Comparative Biochemistry and Physiology Part A Physiology · 1991 · 67 citations

Life Sciences, Biology, Microbiology +17