Karen Miller‐Moslin

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 325 citations · Full text

Selective Smoothened Antagonist, Chemoprevention Strategy, Novel Therapy +14

Regioselectivity and enantioselectivity in nickel-catalysed reductive coupling reactions of alkynes

Ryan M. Moslin, Karen Miller‐Moslin, Timothy F. Jamison · Chemical Communications · 2007 · 219 citations · Full text

Chemical Engineering, Cross-coupling Reaction, Engineering +11

1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

Karen Miller‐Moslin, Stefan Peukert, Rishi K. Jain et al. · Journal of Medicinal Chemistry · 2009 · 106 citations · Full text

Pharmaceutical Science, Antitumor Activity, Pharmacotherapy +16

Discovery of NVP‐LEQ506, a Second‐Generation Inhibitor of Smoothened

Stefan Peukert, Feng He, Miao Dai et al. · ChemMedChem · 2013 · 88 citations

Molecular Pharmacology, Continued Optimization, Competitor Compound +15

The Role of the Acidity of N-Heteroaryl Sulfonamides as Inhibitors of Bcl-2 Family Protein–Protein Interactions

B. Barry Touré, Karen Miller‐Moslin, Naeem Yusuff et al. · ACS Medicinal Chemistry Letters · 2013 · 72 citations · Full text

Combinatorial Chemistry, Antiapoptotic Members, Heterocycle Chemistry +16