Stefan Peukert

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 553 citations

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 325 citations · Full text

Selective Smoothened Antagonist, Chemoprevention Strategy, Novel Therapy +14

Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer

George S. Tria, Tinya J. Abrams, Jason R. Baird et al. · Journal of Medicinal Chemistry · 2018 · 123 citations · Full text

Oral Bioavailability, Breast Oncology, Chemoprevention Strategy +16

1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

Karen Miller‐Moslin, Stefan Peukert, Rishi K. Jain et al. · Journal of Medicinal Chemistry · 2009 · 106 citations · Full text

Pharmaceutical Science, Antitumor Activity, Pharmacotherapy +16

Molecular Basis for Kv1.5 Channel Block

Niels Decher, Bernard Pirard, Florian Bundis et al. · Journal of Biological Chemistry · 2003 · 103 citations · Full text

Cardiac Muscle, Kv1.5 Channels, Molecular Biology +19