Paul Clark

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

Lupeng Ye, Jonathan J. Park, Lei Peng et al. · Cell Metabolism · 2022 · 181 citations · Full text

Car-t Therapy, Immunology, Genetic Engineering +8

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Guangchuan Wang, Ryan D. Chow, Lvyun Zhu et al. · Cancer Discovery · 2020 · 133 citations · Full text

Increased ICAM-1 Expression Causes Endothelial Cell Leakiness, Cytoskeletal Reorganization and Junctional Alterations

Paul Clark, Thomas D. Manes, Jordan S. Pober et al. · Journal of Investigative Dermatology · 2006 · 119 citations · Full text

Inflammation, Endothelial Cell Pathobiology, Cytokine +14

Claudin-5 Controls Intercellular Barriers of Human Dermal Microvascular but Not Human Umbilical Vein Endothelial Cells

Martin S. Kluger, Paul Clark, George Tellides et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2013 · 86 citations · Full text

Tumor Necrosis Factor Disrupts Claudin-5 Endothelial Tight Junction Barriers in Two Distinct NF-κB-Dependent Phases

Paul Clark, Richard Kim, Jordan S. Pober et al. · PLoS ONE · 2015 · 83 citations · Full text