Jonathan J. Park

Comprehensive functional genomic resource and integrative model for the human brain

Daifeng Wang, Shuang Liu, Jonathan Warrell et al. · Science · 2018 · 1K citations · Full text

Neurogenomics, Genetics, Genetic Epidemiology +26

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Matthew B. Dong, Guangchuan Wang, Ryan D. Chow et al. · Cell · 2019 · 308 citations · Full text

Off-target Effect, Genome Surgery, Cd8 T Cells +11

In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

Lupeng Ye, Jonathan J. Park, Matthew B. Dong et al. · Nature Biotechnology · 2019 · 201 citations

Glioma, Cd8 T Cells, Immunology +10

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

Shuai Yuan, Lei Peng, Jonathan J. Park et al. · Molecular Cell · 2020 · 196 citations · Full text

Viral Replication, Pathogenesis, Viral Pathogenesis +8

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

Lupeng Ye, Jonathan J. Park, Lei Peng et al. · Cell Metabolism · 2022 · 181 citations · Full text

Car-t Therapy, Immunology, Genetic Engineering +8