Ryan D. Chow

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Matthew B. Dong, Guangchuan Wang, Ryan D. Chow et al. · Cell · 2019 · 308 citations · Full text

Off-target Effect, Genome Surgery, Cd8 T Cells +11

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes

Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque et al. · PLoS Biology · 2021 · 267 citations · Full text

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

Ryan D. Chow, Christopher D. Guzman, Guangchuan Wang et al. · Nature Neuroscience · 2017 · 243 citations · Full text

Off-target Effect, Glioma, Genome Engineering +8

In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

Lupeng Ye, Jonathan J. Park, Matthew B. Dong et al. · Nature Biotechnology · 2019 · 201 citations

Glioma, Cd8 T Cells, Immunology +10

Parent stem cells can serve as niches for their daughter cells

Ana Pardo–Saganta, Purushothama Rao Tata, Brandon M. Law et al. · Nature · 2015 · 194 citations

Embryonic Stem Cell, Developmental Biology, Cell Division +10