Guangchuan Wang

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Matthew B. Dong, Guangchuan Wang, Ryan D. Chow et al. · Cell · 2019 · 327 citations · Full text

Life Sciences, Genetics, Immunology +16

Development of a prognostic score for recommended TACE candidates with hepatocellular carcinoma: A multicentre observational study

Qiuhe Wang, Dongdong Xia, Wei Bai et al. · Journal of Hepatology · 2019 · 266 citations

Medicine, Oncology, Hepatology +13

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

Ryan D. Chow, Christopher D. Guzman, Guangchuan Wang et al. · Nature Neuroscience · 2017 · 247 citations · Full text

Medicine, Molecular Genetics, Oncology +10

In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

Lupeng Ye, Jonathan J. Park, Matthew B. Dong et al. · Nature Biotechnology · 2019 · 206 citations

Medicine, Immunology, Oncology +14

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

Chengsong Yan, Lin Zheng, Shutan Jiang et al. · Cancer Cell · 2023 · 205 citations · Full text

Life Sciences, Cancer Biology, Immunology +16