Chengsong Yan

Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism

Wei Yang, Yibing Bai, Ying Xiong et al. · Nature · 2016 · 967 citations · Full text

Inflammation, Cholesterol Metabolism, Medicine +10

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

Chengsong Yan, Lin Zheng, Shutan Jiang et al. · Cancer Cell · 2023 · 174 citations · Full text

Inflammation, Exhaustion-associated Cholesterol Deficiency, Oxysterol +11

Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling

Lunyi Li, Xingdong Guo, Xiaoshan Shi et al. · Proceedings of the National Academy of Sciences · 2017 · 108 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +18

Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor

Xingdong Guo, Chengsong Yan, Hua Li et al. · Cell Research · 2017 · 51 citations · Full text

Proteinlipid Interaction, Signal Transduction, G Protein-coupled Receptor +10

Shaping immune landscape of colorectal cancer by cholesterol metabolites

Yibing Bai, Tongzhou Li, Qinshu Wang et al. · EMBO Molecular Medicine · 2024 · 18 citations · Full text