Concepedia

Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism

Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu,

Nature · 2016 · 1K citations · 21 references

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21

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Paul C. Tumeh, Christina L. Harview, Jennifer H. Yearley et al. · Nature · 2014 · 6.6K citations · Full text

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The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui, Shannon K. Bromley, Cenk Sumen et al. · Science · 1999 · 3.1K citations

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Allogeneic stimulation of cytotoxic T cells by supported planar membranes.

A A Brian, Harden M. McConnell · Proceedings of the National Academy of Sciences · 1984 · 794 citations · Full text

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TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

Björn F. Lillemeier, Manuel Mörtelmaier, Martin B. Forstner et al. · Nature Immunology · 2009 · 637 citations

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Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

Yoko Kidani, Heidi Elsaesser, M. Benjamin Hock et al. · Nature Immunology · 2013 · 546 citations · Full text

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