Lei Peng

In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

Lupeng Ye, Jonathan J. Park, Matthew B. Dong et al. · Nature Biotechnology · 2019 · 206 citations

Medicine, Immunology, Oncology +14

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

Shuai Yuan, Lei Peng, Jonathan J. Park et al. · Molecular Cell · 2020 · 204 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +14

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

Lupeng Ye, Jonathan J. Park, Lei Peng et al. · Cell Metabolism · 2022 · 191 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Resveratrol Inhibits β-Amyloid-Induced Neuronal Apoptosis through Regulation of SIRT1-ROCK1 Signaling Pathway

Xiaowen Feng, Nan Liang, Dexiao Zhu et al. · PLoS ONE · 2013 · 155 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Antitumor and anti-angiogenesis effects of thymoquinone on osteosarcoma through the NF-κB pathway

Lei Peng, An Liu, Yue Shen et al. · Oncology Reports · 2012 · 149 citations · Full text

Medicine, Oncology, Pharmacology +14