Lvyun Zhu

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Matthew B. Dong, Guangchuan Wang, Ryan D. Chow et al. · Cell · 2019 · 327 citations · Full text

Life Sciences, Genetics, Immunology +16

Genome Sequencing of the Perciform Fish Larimichthys crocea Provides Insights into Molecular and Genetic Mechanisms of Stress Adaptation

Jingqun Ao, Yinnan Mu, Li‐xin Xiang et al. · PLoS Genetics · 2015 · 313 citations · Full text

Life Sciences, Biology, Genetics +15

B Cells in Teleost Fish Act as Pivotal Initiating APCs in Priming Adaptive Immunity: An Evolutionary Perspective on the Origin of the B-1 Cell Subset and B7 Molecules

Lvyun Zhu, Aifu Lin, Tong Shao et al. · The Journal of Immunology · 2014 · 149 citations

Life Sciences, Evolutionary Biology, Immunology +17

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Guangchuan Wang, Ryan D. Chow, Lvyun Zhu et al. · Cancer Discovery · 2020 · 144 citations · Full text

Medicine, Cancer Biology, Oncology +17

Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity

Guangchuan Wang, Ryan D. Chow, Zhigang Bai et al. · Nature Immunology · 2019 · 121 citations

Life Sciences, Genetics, Molecular Genetics +14