A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors <i>in vitro</i> and <i>in vivo</i>

Ikuo Mitsui, Eiji Kumazawa, Yasuhide Hirota, +7

Japanese Journal of Cancer Research

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure–activity relationships

Takao Horiuchi, Jun Chiba, Kouichi Uoto, +1

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural Sciences +8

Synthesis and Structure-Activity Relationships of Novel 2',2'-Difluoro Analogues of Docetaxel.

Kouichi Uoto, Satoru Ohsuki, H. TAKENOSHITA, +6

Chemical and Pharmaceutical Bulletin

Pharmaceutical ScienceSeveral 2',2'-Difluoro DerivativesOrganic ChemistryPharmacotherapyChemistry +16

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure–activity relationships. Part 2

Takao Horiuchi, Motoko Nagata, Mayumi Kitagawa, +2

Bioorganic & Medicinal Chemistry

Medicinal ChemistryBiochemistryPart 2MedicineNatural Sciences +8

A Useful Method for Deprotection of the Protective Allyl Group at the Anomeric Oxygen of Carbohydrate Moieties Using Tetrakis(triphenylphosphine)palladium.

Kiyoshi Nakayama, Kouichi Uoto, Kunio Higashi, +2

Chemical and Pharmaceutical Bulletin

Bioorganic ChemistryEngineeringGlycobiologyOrganic ChemistryComplex Allyl Glycosides +14

Antitumor Agents. VII. Synthesis and Antitumor Activity of Novel Hexacyclic Camptothecin Analogs

Masamichi Sugimori, Akio Ejima, Satoru Ohsuki, +6

Journal of Medicinal Chemistry

Hexacyclic Ring SystemMedicinal ChemistryPharmaceutical ScienceAntitumor ActivityHexacyclic Compounds +12

Synthesis and Antitumor Activity of Ring A- and F-Modified Hexacyclic Camptothecin Analogues

Masamichi Sugimori, Akio Ejima, Satoru Ohsuki, +6

Journal of Medicinal Chemistry

Bioorganic ChemistryAntitumor ActivityF-modified Hexacyclic AnaloguesOrganic ChemistryPharmacotherapy +16

Design, synthesis, and biological activity of piperidine diamine derivatives as factor Xa inhibitor

Akiyoshi Mochizuki, Yumi Nakamoto, Hiroyuki Naito, +2

Bioorganic & Medicinal Chemistry Letters

Biological ActivityCombinatorial ChemistryMedicinal ChemistryBiochemistryPiperidine Diamine Derivatives +9

Discovery of Novel Thieno[2,3-d]pyrimidin-4-yl Hydrazone-Based Cyclin-Dependent Kinase 4 Inhibitors: Synthesis, Biological Evaluation and Structure-Activity Relationships

Takao Horiuchi, Yasuyuki Takeda, Noriyasu Haginoya, +5

Chemical and Pharmaceutical Bulletin

Inhibition of ergosterol synthesis by novel antifungal compounds targeting C-14 reductase

Masato Hata, Yoshikazu Ishii, Eri Watanabe, +5

Medical Mycology

Ergosterol SynthesisBiosynthesisAminopiperidine DerivativesAntifungal AgentBiochemistry +12