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Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure–activity relationships

Medicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural SciencesRational Drug DesignCyclin D1-cdk4Biological EvaluationStructure–activity RelationshipsDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery