Samir N. Khleif

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

Samir N. Khleif, James DeGregori, Carole Yee et al. · Proceedings of the National Academy of Sciences · 1996 · 360 citations · Full text

Retinoblastoma Protein, Cell Cycle, Protein P16ink4a +16

Randomized Phase II Trial of Nivolumab Versus Nivolumab and Ipilimumab for Recurrent or Persistent Ovarian Cancer: An NRG Oncology Study

Dmitriy Zamarin, Robert A. Burger, Michael W. Sill et al. · Journal of Clinical Oncology · 2020 · 329 citations · Full text

PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance

Vivek Verma, Rajeev Shrimali, Shamim Ahmad et al. · Nature Immunology · 2019 · 320 citations · Full text

Cancer Immunosurveillance, Pd-1 Blockade, Subprimed Cd8 Cells +10

CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine.

Gregory A. Otterson, Samir N. Khleif, Wei Chen et al. · PubMed · 1995 · 216 citations

AACR-FDA-NCI Cancer Biomarkers Collaborative Consensus Report: Advancing the Use of Biomarkers in Cancer Drug Development

Samir N. Khleif, James H. Doroshow, William N. Hait · Clinical Cancer Research · 2010 · 186 citations

Cancer Management, Pathology, Cancer Registration +18