Ikuo Mitsui

A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors <i>in vitro</i> and <i>in vivo</i>

Ikuo Mitsui, Eiji Kumazawa, Yasuhide Hirota et al. · Japanese Journal of Cancer Research · 1995 · 160 citations · Full text

Synthesis and Structure-Activity Relationships of Novel 2',2'-Difluoro Analogues of Docetaxel.

Kouichi Uoto, Satoru Ohsuki, H. TAKENOSHITA et al. · Chemical and Pharmaceutical Bulletin · 1997 · 80 citations · Full text

Pharmaceutical Science, Several 2',2'-Difluoro Derivatives, Organic Chemistry +18

DX-8951F, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant

Noriko Joto, Mineko Ishii, Megumi Minami et al. · International Journal of Cancer · 1997 · 70 citations · Full text

Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6

Michio Iwahana, Ikuo Mitsui, Akiko Tohgo et al. · Anti-Cancer Drugs · 2000 · 65 citations

Glutathione Content, Metronomic Chemotherapy, Tumor Biology +16

Antitumor Agents. VII. Synthesis and Antitumor Activity of Novel Hexacyclic Camptothecin Analogs

Masamichi Sugimori, Akio Ejima, Satoru Ohsuki et al. · Journal of Medicinal Chemistry · 1994 · 47 citations

Hexacyclic Ring System, Medicinal Chemistry, Pharmaceutical Science +14