Concepedia

Yasuhide Hirota

YH

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Publications

14

Citations

1.8K

H-Index

14

Active since

1987

Affiliations

Daiichi-Sankyo (Japan)(Current)

Daiichi University of Pharmacy

Daiichi Sankyo (Germany)

Okayama University

Yasuhide Hirota is an author at Daiichi-Sankyo (Japan) specializing in medicine, pharmacology, and cancer pharmacology.

Publications per year

1987–2022

14

Publications

14

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.

Yasuyoshi Kawato, Masashi Aonuma, Yasuhide Hirota et al. · PubMed · 1991 · 874 citations

Medicine, Oncology, Pharmacology +13

Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death.

Akiko Yoshioka, S Tanaka, Osamu Hiraoka et al. · Journal of Biological Chemistry · 1987 · 254 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors <i>in vitro</i> and <i>in vivo</i>

Ikuo Mitsui, Eiji Kumazawa, Yasuhide Hirota et al. · Japanese Journal of Cancer Research · 1995 · 163 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity

Junya Kawai, Tadashi Toki, Masahiro Ota et al. · Journal of Medicinal Chemistry · 2019 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Imbalance of deoxyribonucleoside triphosphates, DNA double-strand breaks, and cell death caused by 2-chlorodeoxyadenosine in mouse FM3A cells.

Yasuhide Hirota, Akiko Yoshioka, Shohei Tanaka et al. · PubMed · 1989 · 89 citations

Life Sciences, Molecular Biology, Apoptosis +15

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