Masashi Aonuma

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.

Yasuyoshi Kawato, Masashi Aonuma, Yasuhide Hirota et al. · PubMed · 1991 · 874 citations

Medicinal Chemistry, Chemoprevention Strategy, Camptothecin Derivative Cpt-11 +12

Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor.

Asako Sakaue‐Sawano, Tomoko Takahashi, Sachiko Yamaguchi et al. · PubMed · 1996 · 294 citations

Immunology, Pathology, Angiogenesis +16

Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice

Yasuyoshi Kawato, T Furuta, Masashi Aonuma et al. · Cancer Chemotherapy and Pharmacology · 1991 · 163 citations

Tumor Biology, Antitumor Activity, Nude Mice +8

A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors <i>in vitro</i> and <i>in vivo</i>

Ikuo Mitsui, Eiji Kumazawa, Yasuhide Hirota et al. · Japanese Journal of Cancer Research · 1995 · 160 citations · Full text

E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines

Mayumi Kitagawa, Masashi Aonuma, S H Lee et al. · Oncogene · 2008 · 87 citations · Full text

Tumor Biology, Mdm2 Antagonist-induced Apoptosis, Apoptosis +10