Tadashi Toki

Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity

Junya Kawai, Tadashi Toki, Masahiro Ota et al. · Journal of Medicinal Chemistry · 2019 · 80 citations · Full text

Spontaneous Reporting on Adverse Events by Consumers in the United States: An Analysis of the Food and Drug Administration Adverse Event Reporting System Database

Tadashi Toki, Shunsuke Ono · Drugs - Real World Outcomes · 2018 · 74 citations · Full text

Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold

Junya Kawai, Masahiro Ota, Hitoshi Ohki et al. · ACS Medicinal Chemistry Letters · 2019 · 46 citations · Full text

Combinatorial Chemistry, Aldehyde Dehydrogenase, Biochemistry +13

Lipopolysaccharide accelerates collagen‐induced arthritis in association with rapid and continuous production of inflammatory mediators and anti‐type <scp>II</scp> collagen antibody

Shinji Tanaka, Tadashi Toki, Toshihiko Akimoto et al. · Microbiology and Immunology · 2013 · 26 citations

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: Exploration of effective compounds in arthritis models

H. Shimizu, Tomonori Yamasaki, Yoshiyuki Yoneda et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 24 citations · Full text

Rheumatology, Anti-inflammatory, Biochemistry +10