Hitoshi Ohki

Communication: Synthetic Studies on Sialoglycoconjugates 25: Reactivity of Glycosyl Promoters in α-Glycosylation of N-Acetyl-Neuraminic Acid with the Primary and Secondary Hydroxyl Groups in the Suitably Protected Galactose and Lactose Derivatives

Akira Hasegawa, Takao Nagahama, Hitoshi Ohki et al. · Journal of Carbohydrate Chemistry · 1991 · 161 citations

Bioorganic Chemistry, Engineering, Glycobiology +16

A facile, large-scale preparation of the methyl 2-thioglycoside of N-acetylneuraminic acid, and its usefulness for the α-stereoselective synthesis of sialoglycosides

Akira Hasegawa, Hitoshi Ohki, Takao Nagahama et al. · Carbohydrate Research · 1991 · 150 citations

Engineering, Biochemistry, N-acetylneuraminic Acid +9

Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity

Junya Kawai, Tadashi Toki, Masahiro Ota et al. · Journal of Medicinal Chemistry · 2019 · 80 citations · Full text

Synthetic Studies on Sialoglycoconjugates 41: A Facile Total Synthesis of Ganglioside GM₂

Akira Hasegawa, Takao Nagahama, Hitoshi Ohki et al. · Journal of Carbohydrate Chemistry · 1992 · 59 citations

Bioorganic Chemistry, Ganglioside Gm2, Glycobiology +17

Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold

Junya Kawai, Masahiro Ota, Hitoshi Ohki et al. · ACS Medicinal Chemistry Letters · 2019 · 46 citations · Full text

Combinatorial Chemistry, Aldehyde Dehydrogenase, Biochemistry +13