Hiskias G. Keizer

Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB₁ Cannabinoid Receptor Antagonists

Jos H.M. Lange, Hein K. A. C. Coolen, Herman H. van Stuivenberg et al. · Journal of Medicinal Chemistry · 2003 · 186 citations · Full text

Drug Target, Biological Properties, X-ray Diffraction Study +21

Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant:  Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB₁Cannabinoid Receptor Antagonists

Jos H.M. Lange, Herman H. van Stuivenberg, Hein K. A. C. Coolen et al. · Journal of Medicinal Chemistry · 2004 · 177 citations · Full text

Pyrazole Series, Organic Chemistry, Pharmacotherapy +19

Pomegranate seed oil, a rich source of punicic acid, prevents diet-induced obesity and insulin resistance in mice

Irene O.C.M. Vroegrijk, Janna A. van Diepen, Sjoerd A.A. van den Berg et al. · Food and Chemical Toxicology · 2011 · 176 citations · Full text

Obesity, Metabolic Syndrome, Nutrition +9

The effect of Korean pine nut oil on in vitro CCK release, on appetite sensations and on gut hormones in post-menopausal overweight women

Wilrike J. Pasman, Jos Heimerikx, Carina M. Rubingh et al. · Lipids in Health and Disease · 2008 · 146 citations · Full text

Alloantigen Recognition Is Preceded by Nonspecific Adhesion of Cytotoxic T Cells and Target Cells

Hergen Spits, Wim van Schooten, Hiskias G. Keizer et al. · Science · 1986 · 143 citations