Joseph S. Warmus

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Jeffrey F. Ohren, Huifen Chen, A.G. Pavlovsky et al. · Nature Structural & Molecular Biology · 2004 · 612 citations

Signal Transduction, Signaling Pathway, Cell Regulation +8

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

Stephen D. Barrett, Alexander J. Bridges, David T. Dudley et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 280 citations

Medicinal Chemistry, Drug Target, Biochemistry +10

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

Matthew F. Brown, Usa Reilly, J. A. Abramite et al. · Journal of Medicinal Chemistry · 2011 · 97 citations · Full text

A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs

Elizabeth A. Lunney, Susan E. Hagen, John M. Domagala et al. · Journal of Medicinal Chemistry · 1994 · 89 citations · Full text

Enantioselective synthesis of the bottom half of chlorothricolide. 3. Studies of the steric directing group strategy for stereocontrol in intramolecular Diels-Alder reactions

William Roush, Masanori Kageyama, Renata Riva et al. · The Journal of Organic Chemistry · 1991 · 73 citations

Halogenation, Engineering, Altmetric Attention Score +11