Darin J. Gustin

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

Structure guided design of a series of sphingosine kinase (SphK) inhibitors

Darin J. Gustin, Yihong Li, Matthew L. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 98 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9

Design, Synthesis, and in Vitro Evaluation of Dipeptide-Based Antibody Minor Groove Binder Conjugates

Scott C. Jeffrey, Michael Torgov, Jamie B. Andreyka et al. · Journal of Medicinal Chemistry · 2005 · 89 citations

Heavy Atom Isotope Effects Reveal a Highly Polarized Transition State for Chorismate Mutase

Darin J. Gustin, Patrizio Mattei, Peter Kast et al. · Journal of the American Chemical Society · 1999 · 88 citations

Chorismate Mutase, Biochemistry, Natural Sciences +10

Sphingosine Kinase Activity Is Not Required for Tumor Cell Viability

Karen Rex, Shawn Jeffries, Matthew L. Brown et al. · PLoS ONE · 2013 · 65 citations · Full text

Chemoprevention Strategy, Apoptosis, Cell Death +18