Patrizio Mattei

A novel antibiotic class targeting the lipopolysaccharide transporter

Claudia Zampaloni, Patrizio Mattei, Konrad Bleicher et al. · Nature · 2024 · 259 citations · Full text

Pharmacological Promiscuity: Dependence on Compound Properties and Target Specificity in a Set of Recent Roche Compounds

Jens‐Uwe Peters, Patrick Schnider, Patrizio Mattei et al. · ChemMedChem · 2009 · 149 citations

Drug Target, Pharmacological Study, Biochemistry +10

A new antibiotic traps lipopolysaccharide in its intermembrane transporter

Karanbir S. Pahil, Morgan S. A. Gilman, Vadim Baidin et al. · Nature · 2024 · 138 citations · Full text

An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes

Sufyan G. Sayyed, Mi Heon Ryu, Onkar P. Kulkarni et al. · Kidney International · 2011 · 127 citations · Full text

Inflammation, Glomerulonephritis, Metabolic Syndrome +13

A Real-World Perspective on Molecular Design

Bernd Kuhn, Wolfgang Guba, Jérôme Hert et al. · Journal of Medicinal Chemistry · 2016 · 119 citations · Full text

Drug Target, Hit Identification, Molecular Biology +20