Wolfgang Guba - Concepedia

Author

Wolfgang Guba

Roche (Switzerland)ORCID

Also Known As

Guba, W., Guba, Wolfgang, Uwe Grether, W GUBA, W Guba, W. GUBA, W. Guba, Wolfgang GUBA, Wolfgang Guba

132

Publications

3.5K

Citations

H-Index

Concepts

All Affiliations

Roche (Switzerland)ETH Zurich Universität Hamburg European Brain Research Institute University of L'Aquila

About

Wolfgang Guba is an author at Roche (Switzerland) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	23	31	2.2K
2	Natural Sciences	17	18	1K
3	Engineering	7	7	574
4	Social Sciences	2	2	97
5	Health Sciences	1	1	24

Wolfgang Guba

Publications

3.1K

Citations

H-Index

Page 1

	Year	Citations
VolSurf: a new tool for the pharmacokinetic optimization of lead compounds Gabriele Cruciani, Manuel Pastor, Wolfgang Guba European Journal of Pharmaceutical Sciences Lead CompoundsPharmaceutical SciencePharmaceutical ResearchNew ToolMedicine	2000	426
Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries Olivier Roche, Petra Schneider, Jochen Zuegge, Journal of Medicinal Chemistry EngineeringHit IdentificationPattern DiscoveryNonlinear Statistical MethodsMedicinal Chemistry	2001	250
Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7 K. Jaeger, S. Bruenle, Tobias Weinert, Cell	2019	141
β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease Hans Hilpert, Wolfgang Guba, Thomas J. Woltering, Journal of Medicinal Chemistry Neurochemical BiomarkersPharmacotherapyAlzheimer ’Pre-clinical PharmacologyMolecular Pharmacology	2013	136
Torsion Angle Preferences in Druglike Chemical Space: A Comprehensive Guide Christin Schärfer, Tanja Schulz‐Gasch, Hans‐Christian Ehrlich, Journal of Medicinal Chemistry Torsion LibraryPharmaceutical ScienceBiomolecular Structure PredictionTorsion PatternMolecular Biology	2013	134
A Real-World Perspective on Molecular Design Bernd Kuhn, Wolfgang Guba, Jérôme Hert, Journal of Medicinal Chemistry Drug TargetHit IdentificationMolecular BiologyComputational ChemistryRoche Research Projects	2016	119
Structural insights into the inhibition of glycine reuptake Azadeh Shahsavar, Peter Stohler, Gleb Bourenkov, Nature BiochemistryG Protein-coupled ReceptorGlycine ReuptakePharmacologyCarbohydrate-protein Interaction	2021	106
New evidence for a membrane-bound pathway in hormone receptor binding Luis Moroder, Roberta Romanò, Wolfgang Guba, Biochemistry	1993	94
Combined Approach of NMR and Molecular Dynamics within a biphasic Membrane Mimetic: Conformation and Orientation of the Bradykinin Antagonist Hoe 140 Wolfgang Guba, Gerd Breipohl, Stefan Henke, Journal of the American Chemical Society Proteinlipid InteractionEngineeringBiphasic Membrane MimeticAltmetric Attention ScorePeptide Science	1994	81
Recent developments in de novo design and scaffold hopping. Harald Mauser, Wolfgang Guba PubMed EngineeringMolecular BiologyBiofabricationChemical BiologyMolecular Design	2008	80

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