Paris Ward

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Philip A. Harris, Scott B. Berger, Jae Uk Jeong et al. · Journal of Medicinal Chemistry · 2017 · 475 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

DNA-Encoded Library Screening Identifies Benzo[<i>b</i>][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors

Philip A. Harris, Bryan W. King, Deepak Bandyopadhyay et al. · Journal of Medicinal Chemistry · 2016 · 275 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

Anne Cleasby, Jeff Yon, Philip J. Day et al. · PLoS ONE · 2014 · 254 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis

Philip A. Harris, Deepak Bandyopadhyay, Scott B. Berger et al. · ACS Medicinal Chemistry Letters · 2013 · 137 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

Jingsong Yang, Nino Campobasso, Mangatt P. Biju et al. · Chemistry & Biology · 2011 · 116 citations

Life Sciences, Cell Biology, Molecular Biology +9