N-3 Long-Chain Polyunsaturated Fatty Acid Supplementation Significantly Reduces Liver Oxidative Stress in High Fat Induced Steatosis

Rodrigo Valenzuela, Alejandra Espinosa, Daniel Gonzalez‐Mañán, +4

PLoS ONE

NutritionFatty Liver DiseaseCaloric RestrictionExperimental NutritionOxidative Stress +15

<i>N-3</i>long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-α upregulation and NF-κB DNA binding abrogation

Gladys Tapia, Rodrigo Valenzuela, Alejandra Espinosa, +5

Molecular Nutrition & Food Research

Reversal of high-fat diet-induced hepatic steatosis by n-3 LCPUFA: role of PPAR-α and SREBP-1c

Camila G. Dossi, Gladys Tapia, Alejandra Espinosa, +2

The Journal of Nutritional Biochemistry

Metabolic SyndromeMetabolic Associated SteatohepatitisHepatologyLipid NutritionLiver Physiology +10

Bioconversion of α-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with α-linolenic acid-rich oils

Daniel Gonzalez‐Mañán, Gladys Tapia, Juan G. Gormaz, +6

Food & Function

Calcium‐sensing receptor activates the NLRP3 inflammasome in LS14 preadipocytes mediated by ERK1/2 signaling

Amanda D’Espessailles, Yuly A. Mora, Cecilia Fuentes, +1

Journal of Cellular Physiology

ImmunologyRenal InflammationImmune RegulationCasr ActivationCellular Physiology +21

Rosa Mosqueta Oil Prevents Oxidative Stress and Inflammation through the Upregulation of PPAR-α and NRF2 in C57BL/6J Mice Fed a High-Fat Diet

Daniel Gonzalez‐Mañán, Amanda D’Espessailles, Camila G. Dossi, +3

Journal of Nutrition

InflammationMetabolic SyndromeC57bl/6j Mice FedBiochemistryMedicine +10

Dietary alpha- and gamma-tocopherol (1:5 ratio) supplementation attenuates adipose tissue expansion, hepatic steatosis, and expression of inflammatory markers in a high-fat-diet–fed murine model

Nevenka Juretić, Ruth Sepúlveda, Amanda D’Espessailles, +5

Nutrition

ObesityMetabolic SyndromeInflammationNutritionLipid Nutrition +11

Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation

Amanda D’Espessailles, Natalia Santillana, Sofía Sanhueza, +2

Molecular and Cellular Endocrinology

InflammationCytokineAnti-inflammatorySignal TransductionAutoimmune Disease +9

Higher hepatic advanced glycation end products and liver damage markers are associated with nonalcoholic steatohepatitis

Kathleen Priken Figueroa, Gladys Tapia, Cynthia Cadagan, +4

Nutrition Research

Metabolic Associated SteatohepatitisLiver Damage MarkersHepatologyNonalcoholic Fatty Liver DiseaseMedicine +12

Hormonal pretreatment preserves liver regenerative capacity and minimizes inflammation after partial hepatectomy

Amanda D’Espessailles, Camila G. Dossi, Giomar Intriago, +2

Annals of Hepatology