John D. McCarter

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

Jude Canon, Karen Rex, Anne Y. Saiki et al. · Nature · 2019 · 2.3K citations

Medicine, Oncology, Pharmacology +14

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

A Structural View of the Action of<i>Escherichia coli</i>(<i>lac</i>Z) β-Galactosidase^,

D.H. Juers, Tom D. Heightman, Andrea Vasella et al. · Biochemistry · 2001 · 230 citations

Life Sciences, Biochemistry, Molecular Biology +16

A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation

Ryan P. Wurz, Ken Dellamaggiore, Hannah Dou et al. · Journal of Medicinal Chemistry · 2017 · 204 citations

Life Sciences, Biochemistry, Molecular Biology +17

The Role of Sugar Substituents in Glycoside Hydrolysis

Mark Namchuk, John D. McCarter, Adam Becalski et al. · Journal of the American Chemical Society · 2000 · 191 citations

Life Sciences, Biochemistry, Chemistry +16