Tom D. Heightman

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.2K citations · Full text

Bet Bromodomains, Genetics, Pathogenesis +3

Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases

Tom D. Heightman, Andrea Vasella · Angewandte Chemie International Edition · 1999 · 539 citations

Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases

Tom D. Heightman, Andrea Vasella · Angewandte Chemie International Edition · 1999 · 506 citations

Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras

Honorine Lebraud, David J. Wright, Christopher N. Johnson et al. · ACS Central Science · 2016 · 383 citations · Full text

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

Tomohiko Kanno, Yuka Kanno, Gary LeRoy et al. · Nature Structural & Molecular Biology · 2014 · 309 citations · Full text

Histone Modifications, Chromatin, Natural Sciences +9