Honorine Lebraud

Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras

Honorine Lebraud, David J. Wright, Christopher N. Johnson et al. · ACS Central Science · 2016 · 396 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Trifluoroacetic Acid in 2,2,2‐Trifluoroethanol Facilitates S_NAr Reactions of Heterocycles with Arylamines

Benoît Carbain, Christopher R. Coxon, Honorine Lebraud et al. · Chemistry - A European Journal · 2014 · 39 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers

Bernard Barlaam, Sabina Cosulich, Bénédicte Delouvrié et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 35 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles

Honorine Lebraud, Christopher R. Coxon, Victoria S. Archard et al. · Organic & Biomolecular Chemistry · 2013 · 25 citations

Life Sciences, Biochemistry, Pharmacology +16

In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor

Honorine Lebraud, David J. Wright, Charlotte East et al. · Molecular BioSystems · 2016 · 22 citations

Life Sciences, Biochemistry, Molecular Biology +15