Benoît Carbain

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines

Christopher R. Coxon, Elizabeth Anscombe, Suzannah J. Harnor et al. · Journal of Medicinal Chemistry · 2016 · 119 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

Gianni Chessari, Ian R. Hardcastle, Jong Sook Ahn et al. · Journal of Medicinal Chemistry · 2021 · 53 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Trifluoroacetic Acid in 2,2,2‐Trifluoroethanol Facilitates S_NAr Reactions of Heterocycles with Arylamines

Benoît Carbain, Christopher R. Coxon, Honorine Lebraud et al. · Chemistry - A European Journal · 2014 · 39 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines

Michaela Hylsová, Benoît Carbain, Jindřich Fanfrlík et al. · European Journal of Medicinal Chemistry · 2016 · 37 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +16

Efficient Synthesis of Highly Active Phospha‐Isosteres of the Influenza Neuraminidase Inhibitor Oseltamivir

Benoît Carbain, Patrick Collins, Lori Callum et al. · ChemMedChem · 2009 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14