L. Danielle Johnston

Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

Scott R. Daigle, Edward J. Olhava, Carly A. Therkelsen et al. · Cancer Cell · 2011 · 934 citations · Full text

Medicine, Medicinal Chemistry, Oncology +10

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Elayne Chan-Penebre, Kristy G. Kuplast, Christina R. Majer et al. · Nature Chemical Biology · 2015 · 546 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666

Kenneth W. Duncan, Nathalie Rioux, P. Ann Boriack‐Sjodin et al. · ACS Medicinal Chemistry Letters · 2015 · 151 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Glucocorticoid Receptor Agonists in Models of Germinal Center Non-Hodgkin Lymphomas

Sarah K. Knutson, Natalie M. Warholic, L. Danielle Johnston et al. · PLoS ONE · 2014 · 74 citations · Full text

Medicine, Oncology, Pharmacology +14

Altered phosphorylation and localization of the A‐type channel, Kv4.2 in status epilepticus

Joaquín N. Lugo, Lyndon Forbes Barnwell, Yajun Ren et al. · Journal of Neurochemistry · 2008 · 74 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17