Concepedia

Systemic Administration of Immunostimulatory DNA Sequences Mediates Reversible Inhibition of Th2 Responses in a Mouse Model of Asthma

David H. Broide, Greg Stachnick, Diego Castaneda, Jyothi Nayar, Marina Miller, Jae Youn Cho, Mark Roman, José Manuel Zubeldia, Tomoko Hyashi, Eyal Raz

Journal of Clinical Immunology · 2001 · 86 citations · 20 references

DOI

Concepts

References

20

CpG Oligodeoxynucleotides Act as Adjuvants that Switch on T Helper 1 (Th1) Immunity

Rose S. Chu, Oleg S. Targoni, Arthur Μ. Krieg et al. · The Journal of Experimental Medicine · 1997 · 1K citations · Full text

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Allergen-specific Th1 cells fail to counterbalance Th2 cell–induced airway hyperreactivity but cause severe airway inflammation

Gesine Hansen, Gerald J. Berry, Rosemarie H. DeKruyff et al. · Journal of Clinical Investigation · 1999 · 633 citations · Full text

, , +15

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

Gunther Hartmann, George J. Weiner, A M Krieg · Proceedings of the National Academy of Sciences · 1999 · 624 citations

, , +17

Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma.

Joel N. Kline, Thomas J. Waldschmidt, Thomas R. Businga et al. · PubMed · 1998 · 550 citations

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Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

Eytan Raz, Helen Tighe, Yukio Sato et al. · Proceedings of the National Academy of Sciences · 1996 · 517 citations

, , +16