Concepedia

Th2 Effector Function

Th2 Effector Function is a type of CD4+ T helper cell-mediated immune response characterized by the secretion of cytokines such as IL-4, IL-5, and IL-13, which collectively promote humoral immunity and activation of B cells, eosinophils, and mast cells while suppressing intracellular pathogen-directed responses.

749

Publications

71.5K

Citations

4.4K

Authors

1.1K

Institutions

Publications per year

2017–2026

93

Parents

Publications

749

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Daniel R. Neill, See Heng Wong, Agustin Bellosi et al. · Nature · 2010 · 2K citations · Full text

, , +14

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

Kazuyo Moro, Taketo Yamada, M. Tanabe et al. · Nature · 2009 · 2K citations

, , +15

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K. Kuchroo, Mercy Prabhu Das, Julia A. Brown et al. · Cell · 1995 · 1.7K citations · Full text

, , +15

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Kazuya Shimoda, Jan van Deursent, Mark Y. Sangster et al. · Nature · 1996 · 1.3K citations

, , +16

IL-25 Induces IL-4, IL-5, and IL-13 and Th2-Associated Pathologies In Vivo

Madeline Fort, Jeanne Cheung, David Yen et al. · Immunity · 2001 · 1.2K citations · Full text

, , +13

1–5 of 749

Authors

4.4K

  1. AN
    Andrew N. J. McKenzie

    MRC Laboratory of Molecular Biology, United Kingdom

    13 publications · 3.7K citations

    13

    h-index

  2. LC
    Lauren Cohn

    Yale University, United States

    11 publications · 2.7K citations

    11

    h-index

  3. FB
    Frank Brombacher

    University of Cape Town, South Africa

    10 publications · 1.4K citations

    10

    h-index

  4. BN
    Bart N. Lambrecht

    Ghent University, Belgium

    9 publications · 1K citations

    9

    h-index

  5. RA
    Richard A. Flavell

    Yale University, United States

    9 publications · 1.3K citations

    9

    h-index

1–5 of 4.4K

Institutions

1.1K

  1. National Institutes of Health

    Bethesda, United States

    25 h-index

    102 publications

    15.8K citations

  2. Yale University

    New Haven, United States

    21 h-index

    100 publications

    19.8K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    20 h-index

    66 publications

    11.4K citations

  4. Harvard University

    Cambridge, United States

    18 h-index

    65 publications

    13.6K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    15 h-index

    43 publications

    14.1K citations

  6. University of California, San Francisco

    San Francisco, United States

    13 h-index

    36 publications

    6.5K citations

  7. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    13 h-index

    39 publications

    23.3K citations

  8. Inserm

    Paris, France

    12 h-index

    50 publications

    4.2K citations

1–8 of 1.1K

Venues

  1. The Journal of Immunology

    JI · 122 publications · 12.4K citations

    62

    h-index

  2. Journal of Allergy and Clinical Immunology

    46 publications · 4K citations

    37

    h-index

  3. The Journal of Experimental Medicine

    22 publications · 4.5K citations

    21

    h-index

  4. Blood

    21 publications · 2.3K citations

    21

    h-index

  5. European Journal of Immunology

    EJI · 26 publications · 1.7K citations

    19

    h-index

1–5