Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

Marco Antonio Meraz‐Ríos, J. Michael White, Kathleen C. F. Sheehan et al. · Cell · 1996 · 1.7K citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +9

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

Joan E. Durbin, Renée Hackenmiller, M. Celeste Simon et al. · Cell · 1996 · 1.6K citations · Full text

IL-4 directs the development of Th2-like helper effectors.

Susan L. Swain, Andrew D. Weinberg, M English et al. · The Journal of Immunology · 1990 · 1.3K citations · Full text

Lymphocyte Development, Immunology, Immune Regulation +17

Generation and Analysis of Interleukin-4 Deficient Mice

Ralf Kühn, Klaus Rajewsky, Werner Müller · Science · 1991 · 1.3K citations

Inflammation, Cytokine, Immunogenetics +13

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

Manfred Köpf, Graham Le Gros, Martin F. Bachmann et al. · Nature · 1993 · 1.2K citations

Inflammation, Cytokine, Autoimmune Disease +9