T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

Enfu Hui, Jeanne Cheung, Jing Zhu, +8

Science

Programmed Cell Death-1Adaptive Immune SystemT-regulatory CellImmunologyCell Death +16

IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

David Yen, Jeanne Cheung, Heleen Scheerens, +12

Journal of Clinical Investigation

Chronic Inflammatory DiseasesImmunologyImmune RegulationPathologyMouse Ibd Studies +15

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

Stefan Pflanz, Jackie C. Timans, Jeanne Cheung, +18

Immunity

InflammationCytokineAutoimmune DiseaseP28 ProteinHeterodimeric Cytokine +9

A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

Christi Parham, Madaline Chirica, Jacqueline Timans, +18

The Journal of Immunology

InflammationCytokineIl-23 ResponsivenessAutoimmune DiseaseIl-12r Subunit Il-12rbeta1 +8

IL-25 Induces IL-4, IL-5, and IL-13 and Th2-Associated Pathologies In Vivo

Madeline Fort, Jeanne Cheung, David Yen, +13

Immunity

InflammationCytokineTh2-associated PathologiesAutoimmune DiseaseIl-25 Induces Il-4 +9

MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade

Peter Ebert, Jeanne Cheung, Yagai Yang, +8

Immunity

Cancer ImmunosurveillanceMedicineReceptor Tyrosine KinaseImmunologyImmune Checkpoint Inhibitor +4

Role of PD-1 during effector CD8 T cell differentiation

Eunseon Ahn, Koichi Araki, Masao Hashimoto, +7

Proceedings of the National Academy of Sciences

Viral ImmunityImmunologyAntiviral ResponseExpression KineticsVirology +11

PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer

Soyoung Oh, Dai-Chen Wu, Jeanne Cheung, +15

Nature Cancer

Cancer ImmunosurveillancePd-l1 ExpressionMedicineT-regulatory CellImmunology +10

Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

Janet Lau, Jeanne Cheung, Armando Navarro, +17

Nature Communications

Masoprocol (nordihydroguaiaretic acid): a new antihyperglycemic agent isolated from the creosote bush (Larrea tridentata)

Jian Luo, T. Chuang, Jeanne Cheung, +9

European Journal of Pharmacology

Bioorganic ChemistryBiochemistryBioassay-guided IsolationNordihydroguaiaretic AcidNatural Sciences +6