Concepedia

Systemic Administration

Systemic Administration is a route of administration that delivers a therapeutic agent into the systemic circulation, thereby allowing widespread distribution throughout the body to achieve a generalized physiological effect.

3.3K

Publications

204.7K

Citations

16.7K

Authors

2.9K

Institutions

Publications per year

2017–2026

477

Parents

Publications

3.3K

Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer

Steven A. Rosenberg, Michael T. Lotze, Linda Muul et al. · New England Journal of Medicine · 1985 · 2.6K citations

, , +15

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

Liya Qin, Xuefei Wu, Michelle L. Block et al. · Glia · 2007 · 2.2K citations · Full text

, , +17

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

F Liu, Young Song, D Liu · Gene Therapy · 1999 · 1.7K citations

, , +15

Brain-Derived Neurotrophic Factor Produces Antidepressant Effects in Behavioral Models of Depression

Yukihiko Shirayama, Andrew C. H. Chen, Shin Nakagawa et al. · Journal of Neuroscience · 2002 · 1.6K citations · Full text

, , +17

Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury

Michael Brines, Pietro Ghezzi, Sonja Keenan et al. · Proceedings of the National Academy of Sciences · 2000 · 1.4K citations

, , +17

1–5 of 3.3K

Authors

16.7K

  1. SA
    Steven A. Rosenberg

    National Cancer Institute, United States

    16 publications · 5K citations

    16

    h-index

  2. JJ
    James J. Mulé

    Moffitt Cancer Center, United States

    11 publications · 2.1K citations

    11

    h-index

  3. RJ
    Rafael J. Tamargo

    Johns Hopkins University, United States

    8 publications · 605 citations

    8

    h-index

  4. HM
    Hiroyuki Mizuguchi

    The University of Osaka, Japan

    7 publications · 422 citations

    7

    h-index

  5. GL
    Gareth Leng

    University of Edinburgh, United Kingdom

    7 publications · 440 citations

    7

    h-index

1–5 of 16.7K

Institutions

2.9K

  1. Inserm

    Paris, France

    38 h-index

    291 publications

    22.5K citations

  2. Harvard University

    Cambridge, United States

    33 h-index

    195 publications

    36.7K citations

  3. National Institutes of Health

    Bethesda, United States

    31 h-index

    151 publications

    14.7K citations

  4. Johns Hopkins University

    Baltimore, United States

    30 h-index

    228 publications

    13.2K citations

  5. University of Pittsburgh

    Pittsburgh, United States

    28 h-index

    150 publications

    22.6K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    28 h-index

    174 publications

    16K citations

  7. Johns Hopkins Medicine

    Baltimore, United States

    26 h-index

    144 publications

    8.2K citations

  8. National Cancer Institute

    Bethesda, United States

    25 h-index

    129 publications

    55.3K citations

1–8 of 2.9K

Venues

  1. PubMed

    Repository · 253 publications · 11.8K citations

    56

    h-index

  2. 47

    h-index

  3. Journal of Neurochemistry

    JNC · 71 publications · 5.8K citations

    46

    h-index

  4. British Journal of Pharmacology

    BJP · 66 publications · 4K citations

    38

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 38 publications · 7.1K citations

    38

    h-index

1–5