Helen Tighe

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

Life Sciences, Biotechnology, Immunology +17

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

Alun Davies, David L. Simmons, G Hale et al. · The Journal of Experimental Medicine · 1989 · 641 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

Eytan Raz, Helen Tighe, Yukio Sato et al. · Proceedings of the National Academy of Sciences · 1996 · 517 citations

Life Sciences, Immunology, Adaptive Immunity +16

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

Maripat Corr, D J Lee, Dennis A. Carson et al. · The Journal of Experimental Medicine · 1996 · 478 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Conjugation of immunostimulatory DNA to the short ragweed allergen Amb a 1 enhances its immunogenicity and reduces its allergenicity

Helen Tighe, Kenji Takabayashi, David H. Schwartz et al. · Journal of Allergy and Clinical Immunology · 2000 · 390 citations · Full text

Life Sciences, Immunology, Molecular Biology +12