Concepedia

Lactate enhances NMNAT1 lactylation to sustain nuclear NAD+ salvage pathway and promote survival of pancreatic adenocarcinoma cells under glucose-deprived conditions

Huimin Huang, Huimin Huang, Shitong Wang, Hongping Xia, Xingling Zhao, Kaiyuan Chen, Guihua Jin, Shipeng Zhou, Zhaoliang Lu, Tongke Chen,

Cancer Letters · 2024 · 72 citations · 34 references

DOI

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References

34

Metabolic regulation of gene expression by histone lactylation

Di Zhang, Zhanyun Tang, He Huang et al. · Nature · 2019 · 3.9K citations · Full text

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On Respiratory Impairment in Cancer Cells

Otto Warbürg · Science · 1956 · 3.2K citations

, , +13

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying et al. · Nature · 2013 · 2K citations · Full text

, , +12

Glucose feeds the TCA cycle via circulating lactate

Sheng Hui, Jonathan M. Ghergurovich, Raphael J. Morscher et al. · Nature · 2017 · 1.7K citations

, , +12

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Jaeseok Han, Sung Hoon Back, Junguk Hur et al. · Nature Cell Biology · 2013 · 1.7K citations

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