Concepedia

Lactate Production

Lactate Production is a metabolic process involving the synthesis of lactate from pyruvate through anaerobic glycolysis, primarily occurring in skeletal muscle cells during periods of limited oxygen availability to regenerate NAD⁺ and sustain ATP production.

4.5K

Publications

287.4K

Citations

19.1K

Authors

3.4K

Institutions

Publications per year

2017–2026

907

Parents

Publications

4.5K

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

Luc Pellerin, Pierre J. Magistretti · Proceedings of the National Academy of Sciences · 1994 · 2.9K citations · Full text

, , +17

Glucose feeds the TCA cycle via circulating lactate

Sheng Hui, Jonathan M. Ghergurovich, Raphael J. Morscher et al. · Nature · 2017 · 1.7K citations

, , +12

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

Pierre Sonveaux, Frédérique Végran, Thies Schroeder et al. · Journal of Clinical Investigation · 2008 · 1.6K citations · Full text

, , +17

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

Stephanos Pavlides, Diana Whitaker‐Menezes, Remedios Castelló-Cros et al. · Cell Cycle · 2009 · 1.4K citations · Full text

, , +17

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

Jae Young Koh, Dennis W. Choi · Journal of Neuroscience Methods · 1987 · 1.3K citations

, , +17

1–5 of 4.5K

Authors

19.1K

  1. BS
    Bengt Saltin

    University of Copenhagen, Denmark

    17 publications · 1.7K citations

    17

    h-index

  2. GA
    George A. Brooks

    University of California, Berkeley, United States

    20 publications · 3.2K citations

    17

    h-index

  3. LP
    Luc Pellerin

    University of Lausanne, Switzerland

    15 publications · 5.8K citations

    15

    h-index

  4. JG
    Jeremy G. Thompson

    The University of Adelaide, Australia

    14 publications · 1.5K citations

    14

    h-index

  5. WC
    William C. Stanley

    Case Western Reserve University, United States

    13 publications · 1K citations

    13

    h-index

1–5 of 19.1K

Institutions

3.4K

  1. University of Pennsylvania

    Philadelphia, United States

    36 h-index

    164 publications

    15.6K citations

  2. Harvard University

    Cambridge, United States

    35 h-index

    195 publications

    31.9K citations

  3. Inserm

    Paris, France

    34 h-index

    251 publications

    16.7K citations

  4. Shanghai Jiao Tong University

    Shanghai, China

    32 h-index

    293 publications

    21.8K citations

  5. University of California, San Francisco

    San Francisco, United States

    31 h-index

    218 publications

    16.5K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    30 h-index

    146 publications

    9.4K citations

  7. Karolinska Institutet

    Stockholm, Sweden

    30 h-index

    123 publications

    7.2K citations

  8. University of Oxford

    Oxford, United Kingdom

    28 h-index

    108 publications

    9.3K citations

1–8 of 3.4K

Venues

  1. Applied and Environmental Microbiology

    AEM · 77 publications · 9.6K citations

    50

    h-index

  2. PubMed

    Repository · 199 publications · 8.7K citations

    46

    h-index

  3. Journal of Biological Chemistry

    JBC · 73 publications · 6.1K citations

    45

    h-index

  4. Biotechnology and Bioengineering

    68 publications · 5K citations

    42

    h-index

  5. Journal of Applied Physiology

    78 publications · 5.2K citations

    41

    h-index

1–5