Jaeseok Han

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Jaeseok Han, Sung Hoon Back, Junguk Hur et al. · Nature Cell Biology · 2013 · 1.6K citations

Transcriptional Regulation, Cell Regulation, Apoptosis +8

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

Sung Hoon Back, Donalyn Scheuner, Jaeseok Han et al. · Cell Metabolism · 2009 · 361 citations · Full text

Redox Signaling, Signal Transduction, Biochemistry +13

IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis

Shiyu Wang, Zhouji Chen, Vivian Lam et al. · Cell Metabolism · 2012 · 223 citations · Full text

Signal Transduction, Signaling Pathway, Biochemistry +13

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

Justin Hassler, Donalyn Scheuner, Shiyu Wang et al. · PLoS Biology · 2015 · 198 citations · Full text

Molecular Regulation, Cellular Physiology, Insulin Signaling +21

HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis.

Ken Ito, Hongjin Bian, M. Rosana S. Molina et al. · The Journal of Experimental Medicine · 1996 · 191 citations · Full text

Histocompatibility, Genetics, Hla Immunogenetics +17