Justin Hassler

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

D. Thomas Rutkowski, Jun Wu, Sung-Hoon Back et al. · Developmental Cell · 2008 · 582 citations · Full text

Reductive Stress, Transcriptional Regulation, Hepatology +14

The unfolded protein response transducer IRE1α prevents ER stress‐induced hepatic steatosis

Kezhong Zhang, Shiyu Wang, Jyoti Malhotra et al. · The EMBO Journal · 2011 · 351 citations · Full text

IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis

Shiyu Wang, Zhouji Chen, Vivian Lam et al. · Cell Metabolism · 2012 · 223 citations · Full text

Signal Transduction, Signaling Pathway, Biochemistry +13

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

Justin Hassler, Donalyn Scheuner, Shiyu Wang et al. · PLoS Biology · 2015 · 198 citations · Full text

Molecular Regulation, Cellular Physiology, Insulin Signaling +21

Nuclear transport of cancer extracellular vesicle-derived biomaterials through nuclear envelope invagination-associated late endosomes

Germana Rappa, Mark F. Santos, Toni M. Green et al. · Oncotarget · 2017 · 76 citations · Full text

Engineering, Extracellular Membrane Vesicles, Extracellular Microvesicles +18